Objectives: To determine whether the decline in selenium intake and selenium status in men in the West of Scotland might be a contributory factor to male subfertility. Patients and methods: Two semen samples were collected from patients attending a subfertility clinic and those patients with samples showing reduced motility were invited to participate in an ethically approved double-blind clinically controlled trial with informed consent. Sixty-nine patients were recruited and received either placebo, selenium alone or selenium plus vitamins A, C and E daily for 3 months. A further semen sample was collected at the end of the trial.
Selenium–vitamin E supplementation in infertile men: effects on semen parameters and pregnancy rate
Selenium–vitamin E supplementation in infertile men: effects on semen parameters and pregnancy rate
Try out PMC Labs and tell us what you think. Learn More. Infertility is an important medical and social problem that has an impact on well-being. A significant development in the last 10 years in the study of human infertility has been the discovery that oxidative sperm DNA damage has a critical role in the etiology of poor semen quality and male infertility. Selenium Se is an essential element for normal testicular development, spermatogenesis, and spermatozoa motility and function. The predominant biochemical action of Se in both humans and animals is to serve as an antioxidant via the Se-dependent enzyme glutathione peroxidase and thus protect cellular membranes and organelles from peroxidative damage.
Many industrialized countries experience a sharp decline in male fertility. Several reasons can be contributed as the underlying cause, however, an increased exposure to chemicals on a daily basis remains one of the prime suspects. As a result many couples are having difficulties conceiving, because of a low sperm quality. The good news is that you can do something to boost your sperm quality with Bio-SelenoQ The two substances CoQ10 and selenium have separately shown great promise on sperm quality, but in particular in combination, scientific studies show statistically significant results.
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